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Prodils such as ifenprodil selectively inhibit NMDA receptors made up of the NR2B subunit by binding in the slot of NTD domains, a internet site that partially overlaps with that of zinc binding 101. Some synthetic compounds hugely selective to the NTD area of NR2B subunits, as traxoprodil, besonprodil, or radiprodil and other extra not too long ag